Expression of programmed cell death ligand in cutaneous squamous cell carcinoma and treatment of locally advanced disease with pembrolizumab
ML Stevenson, CQF Wang, M Abikhair… - JAMA …, 2017 - jamanetwork.com
Importance Limited therapies are available in patients with inoperable locally advanced
cutaneous squamous cell carcinoma (cSCC). Objective To determine the efficacy of
programmed cell death 1 receptor (PD-1) inhibitors in locally advanced cSCC. Design,
Setting, and Participants A single patient with locally advanced cSCC who declined surgery
and radiotherapy underwent treatment with pembrolizumab, an anti–PD-1 antibody, at an
academic dermatologic surgery section and cancer center. The patient was followed up for …
cutaneous squamous cell carcinoma (cSCC). Objective To determine the efficacy of
programmed cell death 1 receptor (PD-1) inhibitors in locally advanced cSCC. Design,
Setting, and Participants A single patient with locally advanced cSCC who declined surgery
and radiotherapy underwent treatment with pembrolizumab, an anti–PD-1 antibody, at an
academic dermatologic surgery section and cancer center. The patient was followed up for …