[HTML][HTML] Emerging therapies targeting intra-organ inflammation in transplantation
Z Solhjou, H Athar, Q Xu, R Abdi - American Journal of Transplantation, 2015 - Elsevier
Over the past several years, the field of transplantation has witnessed significant progress
on several fronts; in particular, achievements have been made in devising novel
immunosuppressive strategies. An under-explored area that may hold great potential to
improve transplantation outcomes is the design of novel strategies to apply specifically to
organs to reduce intra-graft inflammation. A growing body of evidence indicates a key role of
intra-graft inflammatory cascade in potently instigating the alloimmune response. Indeed …
on several fronts; in particular, achievements have been made in devising novel
immunosuppressive strategies. An under-explored area that may hold great potential to
improve transplantation outcomes is the design of novel strategies to apply specifically to
organs to reduce intra-graft inflammation. A growing body of evidence indicates a key role of
intra-graft inflammatory cascade in potently instigating the alloimmune response. Indeed …
