Factors influencing the immune response to hepatitis B vaccine, booster dose guidelines, and vaccine protocol recommendations

FB Hollinger - The American journal of medicine, 1989 - Elsevier
The clinical course and immunodiagnosis of hepatitis B infection is discussed. Immunization
is necessary to prevent the clinical disease, the development of carriers, and the
transmission of the hepatitis B virus to susceptible persons. Host factors that can curtail the
immune response include increasing age, obesity, smoking cigarettes, and having a
medical condition that compromises the immune system. Increasing the dose of vaccine,
administering the inoculations intramuscularly, and giving the vaccine more frequently can …