The extent of intestinal failure-associated liver disease in patients referred for intestinal rehabilitation is associated with increased mortality: an analysis of the Pediatric …

PJ Javid, AP Oron, CP Duggan, RH Squires… - Journal of pediatric …, 2018 - Elsevier
Background The advent of regional multidisciplinary intestinal rehabilitation programs has
been associated with improved survival in pediatric intestinal failure. Yet, the optimal timing
of referral for intestinal rehabilitation remains unknown. We hypothesized that the degree of
intestinal failure-associated liver disease (IFALD) at initiation of intestinal rehabilitation
would be associated with overall outcome. Methods The multicenter, retrospective Pediatric
Intestinal Failure Consortium (PIFCon) database was used to identify all subjects with …