Development of a computer algorithm for the detection of phase singularities and initial application to analyze simulations of atrial fibrillation

R Zou, J Kneller, LJ Leon, S Nattel - Chaos: An Interdisciplinary Journal …, 2002 - pubs.aip.org
Atrial fibrillation (AF) is a common cardiac arrhythmia, but its mechanisms are incompletely
understood. The identification of phase singularities (PSs) has been used to define spiral
waves involved in maintaining the arrhythmia, as well as daughter wavelets. In the past, PSs
have often been identified manually. Automated PS detection algorithms have been
described previously, but when we attempted to apply a previously developed algorithm we
experienced problems with false positives that made the results difficult to use directly. We …