Apelin effects in human splanchnic arteries. Role of nitric oxide and prostanoids

A Salcedo, J Garijo, L Monge, N Fernández… - Regulatory peptides, 2007 - Elsevier
Apelin effects were examined in human splanchnic arteries from liver donors (normal
arteries) and from liver recipients. Segments 3 mm long were obtained from mesenteric
arteries taken from liver donors (normal arteries), and from hepatic arteries taken from
cirrhotic patients undergoing liver transplantation (liver recipients), and the segments were
mounted in organ baths for isometric tension recording. In arteries under resting conditions,
apelin (10− 10–10− 6 M) caused no effect in any of the arteries tested. In arteries …