Apelin was first identified and characterized from bovine stomach extracts as an
endogenous ligand for the APJ receptor. Apelin/APJ system is abundantly present in
peripheral tissues and central nervous system. Apelin plays a broad role in regulating
physiological and pathological functions. Recently, many reports have showed the effects of
apelin on feeding behavior, however the results are inconsistent, due to different
administration routes, animal species, forms of apelin, etc. Apelin has been involved in …