Brain uptake and organ distribution of 11C from 11C-labeled glucose
SC Jones, RH Ackerman, B Hoop Jr, JC Baron… - International Journal of …, 1983 - Elsevier
The time course of the distribution of carbon-11 (11 C, t sol1 2= 20.4 min) in brain after the iv
administration of 11 C-labeled glucose ([11] glucose) was studied in an effort to understand
and explore its behavior in relation to the known factors concerning the catabolic fate of
glucose carbon in the brain. The biodistribution of 11 C from [11 C] glucose was studied in
rats using organ dissection. Human radiation doses were estimated from rat biodistribution
data. All the rat organs except the brain cleared with a half time of 30–60 min. The brain …
administration of 11 C-labeled glucose ([11] glucose) was studied in an effort to understand
and explore its behavior in relation to the known factors concerning the catabolic fate of
glucose carbon in the brain. The biodistribution of 11 C from [11 C] glucose was studied in
rats using organ dissection. Human radiation doses were estimated from rat biodistribution
data. All the rat organs except the brain cleared with a half time of 30–60 min. The brain …