Sequencing and combination of systemic therapy in metastatic renal cell carcinoma

G de Velasco, A Bex, L Albiges, T Powles… - European Urology …, 2019 - Elsevier
Context Introduction of additional new agents targeting the vascular endothelial growth
factor receptor (VEGFR) and immune checkpoint inhibitors (ICIs) has completely modified
the systemic treatment of metastatic renal cell carcinoma (mRCC) during the last years.
Objective A comprehensive (nonsystematic) review to determine the suggested sequence or
combinations for the systemic treatment of mRCC. Evidence acquisition PubMed and
abstracts from main conferences up to December 2018 were reviewed to retrieve the current …