[HTML][HTML] Hematopoietic stem cell engraftment and seeding permits multi-lymphoid chimerism in vascularized bone marrow transplants
M Siemionow, A Klimczak, S Unal, G Agaoglu… - American Journal of …, 2008 - Elsevier
Vascularized bone marrow transplantation (VBMT) across a MHC barrier under a 7-day αβ-
TCR mAb and CsA protocol facilitated multiple hematolymphoid chimerism via trafficking of
the immature (CD90) bone marrow cells (BMC) between donor and recipient compartments.
Early engraftment of donor BMC [BN (RT1 n)] into the recipient BM compartment [LEW (RT1
l)] was achieved at 1 week posttransplant and this was associated with active hematopoiesis
within allografted bone and correlated with high chimerism in the hematolymphoid organs …
TCR mAb and CsA protocol facilitated multiple hematolymphoid chimerism via trafficking of
the immature (CD90) bone marrow cells (BMC) between donor and recipient compartments.
Early engraftment of donor BMC [BN (RT1 n)] into the recipient BM compartment [LEW (RT1
l)] was achieved at 1 week posttransplant and this was associated with active hematopoiesis
within allografted bone and correlated with high chimerism in the hematolymphoid organs …
