[CITATION][C] Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport

LJ Mandel - Annual review of physiology, 1985 - annualreviews.org
Proximal tubular transport accounts for about 70% of the reabsorptive work of the kidney (35,
42). The tubular cells use a variety of metabolic substrates to provide the energy needed for
these transport processes (15), The actual substrates that are metabolized depend on the
substrate mix present in the extracellular environment, on hormonal influences, and on the
metabolic state (eg acid-base) of the animal. Substrates may enter the proximal tubular cells
either through the luminal side, from the glomerular filtrate, or through the basolateral side …