TGFβ signaling: its role in fibrosis formation and myopathies

EM MacDonald, RD Cohn - Current opinion in rheumatology, 2012 - journals.lww.com
EM MacDonald, RD Cohn
Current opinion in rheumatology, 2012journals.lww.com
An increasing number of skeletal myopathies are demonstrating favorable responses to
alterations of the TGFβ signaling pathway. However, future research is needed to fully
understand the downstream molecular signature associated with this pathway in order to
develop more specific targeted therapies.
Summary
An increasing number of skeletal myopathies are demonstrating favorable responses to alterations of the TGFβ signaling pathway. However, future research is needed to fully understand the downstream molecular signature associated with this pathway in order to develop more specific targeted therapies.
Lippincott Williams & Wilkins