Precision medicine approaches to diabetic kidney disease: tissue as an issue

C Gluck, YA Ko, K Susztak - Current diabetes reports, 2017 - Springer
C Gluck, YA Ko, K Susztak
Current diabetes reports, 2017Springer
Abstract Purpose of Review Precision medicine approaches, that tailor medications to
specific individuals has made paradigm-shifting improvements for patients with certain
cancer types. Recent Findings Such approaches, however, have not been implemented for
patients with diabetic kidney disease. Precision medicine could offer new avenues for novel
diagnostic, prognostic and targeted therapeutics development. Genetic studies associated
with multiscalar omics datasets from tissue and cell types of interest of well-characterized …
Purpose of Review
Precision medicine approaches, that tailor medications to specific individuals has made paradigm-shifting improvements for patients with certain cancer types.
Recent Findings
Such approaches, however, have not been implemented for patients with diabetic kidney disease. Precision medicine could offer new avenues for novel diagnostic, prognostic and targeted therapeutics development. Genetic studies associated with multiscalar omics datasets from tissue and cell types of interest of well-characterized cohorts are needed to change the current paradigm.
Summary
In this review, we will discuss precision medicine approaches that the nephrology community can take to analyze tissue samples to develop new therapeutics for patients with diabetic kidney disease.
Springer