Management of side effects of androgen deprivation therapy

M Grossmann, JD Zajac - Endocrinology and Metabolism …, 2011 - endo.theclinics.com
Prostate cancer is the most common solid-organ cancer in men, with a lifetime risk of 1 in 9.
1 The contemporary 5-year relative survival rate for men with all stages of prostate cancer
combined is estimated to be 98.8%. 2 Because of such high rates in cancer-specific survival,
the consideration of treatment-related toxicity assumes major significance. More than 30% of
men with prostate cancer die of cardiovascular disease, which constitutes the most common
cause of mortality in this patient population. 3, 4 Androgen deprivation therapy (ADT) for the …