Currently, it is well established that monocytes are a heterogeneous type of cell consisting of
phenotypically and functionally distinct subpopulations found to be numerically altered in
blood in patients with a wide variety of disease conditions, such as infection, autoimmunity,
respiratory and cardiovascular diseases, and inflammatory disorders. 1, 2 Thus, 3
subpopulations of circulating monocytic cells have been identified based on expression of
the CD14 LPS receptor and the CD16 low-affinity Fc IgG receptor:(1) CD14 hi CD16 …