[HTML][HTML] Salt sensitivity is associated with insulin resistance, sympathetic overactivity, and decreased suppression of circulating renin activity in lean patients with …

MS Yatabe, J Yatabe, M Yoneda, T Watanabe… - The American journal of …, 2010 - Elsevier
Background: The mechanisms by which a derangement of glucose metabolism causes high
blood pressure are not fully understood. Objectives: This study aimed to clarify the relation
between salt sensitivity of blood pressure and insulin resistance, which are important
subcharacteristics of hypertension and impaired glucose metabolism, respectively. Effects
on the renin-angiotensin and sympathetic nervous systems were also studied. Design: The
state of glucose metabolism was assessed by a hyperinsulinemic euglycemic glucose clamp …