An improved Bonferroni procedure for multiple tests of significance
RJ Simes - Biometrika, 1986 - academic.oup.com
RJ Simes
Biometrika, 1986•academic.oup.comA modification of the Bonferroni procedure for testing multiple hypotheses is presented. The
method, based on the ordered p-values of the individual tests, is less conservative than the
classical Bonferroni procedure but is still simple to apply. A simulation study shows that the
probability of a type I error of the procedure does not exceed the nominal significance level,
α, for a variety of multivariate normal and multivariate gamma test statistics. For independent
tests the procedure has type I error probability equal to α. The method appears particularly …
method, based on the ordered p-values of the individual tests, is less conservative than the
classical Bonferroni procedure but is still simple to apply. A simulation study shows that the
probability of a type I error of the procedure does not exceed the nominal significance level,
α, for a variety of multivariate normal and multivariate gamma test statistics. For independent
tests the procedure has type I error probability equal to α. The method appears particularly …
Abstract
A modification of the Bonferroni procedure for testing multiple hypotheses is presented. The method, based on the ordered p-values of the individual tests, is less conservative than the classical Bonferroni procedure but is still simple to apply. A simulation study shows that the probability of a type I error of the procedure does not exceed the nominal significance level, α, for a variety of multivariate normal and multivariate gamma test statistics. For independent tests the procedure has type I error probability equal to α. The method appears particularly advantageous over the classical Bonferroni procedure when several highly-correlated test statistics are involved.
