Complement activation in patients with diabetic nephropathy

XQ Li, DY Chang, M Chen, MH Zhao - Diabetes & Metabolism, 2019 - Elsevier
Aim Emerging evidence has indicated a role of the complement system in the pathogenesis
of diabetic nephropathy (DN), although the pathways of complement activation and their
clinicopathological relevance in DN are as yet unclear. The present study aimed to
investigate levels of various complement components in plasma and urine of DN patients,
and their correlation with clinicopathological parameters. Methods A total of 68 biopsy-
proven DN patients with plasma samples were recruited, including 50 patients who also had …