Prevention and treatment of diabetic renal disease in type 2 diabetes: the BENEDICT study

G Remuzzi, M Macia, P Ruggenenti - Journal of the American …, 2006 - journals.lww.com
Diabetic nephropathy (DN) is the leading cause of end-stage renal failure in Western
countries and carries an increased risk for cardiovascular mortality. Studies have identified a
number of factors that play a part in the development of DN. Among them, hypertension and
proteinuria are the most important. In the early stages of DN, when albumin is present in the
urine in very low quantities (microalbuminuria) and an increase is seen in BP, there is no
loss of filtrate and patients respond well to prophylactic measures. Microalbuminuria is …