[HTML][HTML] Stressing the brain, fattening the body
L Yang, GS Hotamisligil - Cell, 2008 - cell.com
Cell, 2008•cell.com
Obesity is characterized by chronic activation of inflammatory pathways in peripheral
tissues. In this issue, Zhang et al.(2008) demonstrate that inflammation also occurs in the
central nervous system where it disrupts activity of the hypothalamus leading to resistance to
leptin that is mediated by activation of IKK and the endoplasmic reticulum stress response.
tissues. In this issue, Zhang et al.(2008) demonstrate that inflammation also occurs in the
central nervous system where it disrupts activity of the hypothalamus leading to resistance to
leptin that is mediated by activation of IKK and the endoplasmic reticulum stress response.
Obesity is characterized by chronic activation of inflammatory pathways in peripheral tissues. In this issue, Zhang et al. (2008) demonstrate that inflammation also occurs in the central nervous system where it disrupts activity of the hypothalamus leading to resistance to leptin that is mediated by activation of IKK and the endoplasmic reticulum stress response.
cell.com