Formation of long term memory begins with the activation of many disparate signaling
pathways that ultimately impinge on the cellular mechanisms regulating gene expression.
We investigated whether mechanisms regulating chromatin structure were activated during
the early stages of long term memory formation in the hippocampus. Specifically, we
investigated hippocampal histone acetylation during the initial stages of consolidation of
long term association memories in a contextual fear conditioning paradigm. Acetylation of …