[HTML][HTML] Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption

K Anwar, J Iqbal, MM Hussain - Journal of lipid research, 2007 - ASBMB
It is generally believed that vitamin E is absorbed along with chylomicrons. However, we
previously reported that human colon carcinoma Caco-2 cells use dual pathways,
apolipoprotein B (apoB)-lipoproteins and HDLs, to transport vitamin E. Here, we used
primary enterocytes and rodents to identify in vivo vitamin E absorption pathways. Uptake of
[3 H] α-tocopherol by primary rat and mouse enterocytes increased with time and reached a
maximum at 1 h. In the absence of exogenous lipid supply, these cells secreted vitamin E …