Ultrastructural study of the liver in argininosuccinase deficiency
H Travers, JS Reed, JA Kennedy - Pediatric Pathology, 1986 - Taylor & Francis
H Travers, JS Reed, JA Kennedy
Pediatric Pathology, 1986•Taylor & FrancisThe liver of a 19-year-old woman with argininosuccinase deficiency was studied
ultrastructurally under conditions for excellent tissue fixation. Dilated smooth endoplasmic
reticulum and mitochondrial crystalloids were the most prominent abnormalities found.
These features were compared to fine-structural abnormalities found in other disorders of
the Krebs-Henseleit pathway. No change was considered specific or related to subcellular
enzyme localization.
ultrastructurally under conditions for excellent tissue fixation. Dilated smooth endoplasmic
reticulum and mitochondrial crystalloids were the most prominent abnormalities found.
These features were compared to fine-structural abnormalities found in other disorders of
the Krebs-Henseleit pathway. No change was considered specific or related to subcellular
enzyme localization.
The liver of a 19-year-old woman with argininosuccinase deficiency was studied ultrastructurally under conditions for excellent tissue fixation. Dilated smooth endoplasmic reticulum and mitochondrial crystalloids were the most prominent abnormalities found. These features were compared to fine-structural abnormalities found in other disorders of the Krebs-Henseleit pathway. No change was considered specific or related to subcellular enzyme localization.
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