Time course of degeneration and regeneration of myelinated nerve fibres following chronic loose ligatures of the rat sciatic nerve: can nerve lesions be linked to the …
G Guilbaud, M Gautron, F Jazat, H Ratinahirana… - Pain, 1993 - Elsevier
This study of a mononeuropathy of 1–15 weeks (W) duration was induced in rats by setting 4
loose ligatures around the common sciatic nerve. This chronic lesion, in which the continuity
of the nerve was maintained, has been introduced as a model for experimental pain.
Quantitative analyses of teased nerve fibres and a morphometric analysis of semi-thin
transverse sections, were performed and completed by electron microscopic examination.
Morphological changes were observed mainly distal, but also proximal, to the ligatures …
loose ligatures around the common sciatic nerve. This chronic lesion, in which the continuity
of the nerve was maintained, has been introduced as a model for experimental pain.
Quantitative analyses of teased nerve fibres and a morphometric analysis of semi-thin
transverse sections, were performed and completed by electron microscopic examination.
Morphological changes were observed mainly distal, but also proximal, to the ligatures …
