Amniotic fluid analysis for antimicrobial factors
H Thadepalli, PK Gangopadhyay… - International Journal of …, 1982 - Elsevier
The antimicrobial factors in amniotic fluid (AF) were analyzed in 81 women during various
periods of gestation. The AF inhibited the growth of E. coli 026 when the phosphate/zinc
ratio was< 200 or iron≤ 1.2 μg/ml and unbound transferrin was> 40%. A heatstable non-
lysozymal phosphate insensitive cationic protein with molecular weight higher than
transferrin was also found in inhibitory AF. The antimicrobial properties of AF did not
correlate with absolute zinc or lysozyme levels. The AF was non-inhibitory when it …
periods of gestation. The AF inhibited the growth of E. coli 026 when the phosphate/zinc
ratio was< 200 or iron≤ 1.2 μg/ml and unbound transferrin was> 40%. A heatstable non-
lysozymal phosphate insensitive cationic protein with molecular weight higher than
transferrin was also found in inhibitory AF. The antimicrobial properties of AF did not
correlate with absolute zinc or lysozyme levels. The AF was non-inhibitory when it …
