Abstract Background Context Lumbar disc degeneration (LDD) is a major cause of low back
pain, and is a common and disabling condition worldwide. It has been defined and
measured by multiple spine magnetic resonance imaging (MRI) features, but the
heterogeneity among them has never been fully addressed. Purpose This study examined
the intercorrelations, risk factor associations, and single nucleotide polymorphism (SNP)
heritabilities of lumbar disc MRI features in a large-scale sample to classify the different …