Influence of chronic ethanol consumption on the neurological severity in patients with acute cerebral ischemia

A Ducroquet, D Leys, AA Saabi, F Richard… - Stroke, 2013 - Am Heart Assoc
A Ducroquet, D Leys, AA Saabi, F Richard, C Cordonnier, M Girot, D Deplanque, B Casolla
Stroke, 2013Am Heart Assoc
Background and Purpose—We tested the hypothesis that excessive chronic ethanol
consumption is associated with more severe ischemic strokes. Methods—We recruited
patients with supratentorial cerebral ischemia within 48 hours of symptom onset. We defined
heavy drinkers by a weekly consumption of ethanol of≥ 300 g and severe strokes by a
National Institutes of Health Stroke Scale score≥ 6. Results—Of 436 patients, 60 were
heavy drinkers. Being a heavy drinker was independently associated with baseline National …
Background and Purpose
We tested the hypothesis that excessive chronic ethanol consumption is associated with more severe ischemic strokes.
Methods
We recruited patients with supratentorial cerebral ischemia within 48 hours of symptom onset. We defined heavy drinkers by a weekly consumption of ethanol of ≥300 g and severe strokes by a National Institutes of Health Stroke Scale score≥6.
Results
Of 436 patients, 60 were heavy drinkers. Being a heavy drinker was independently associated with baseline National Institutes of Health Stroke Scale scores ≥6 (odds ratio, 2.35; 95% confidence interval, 1.12–5.26; P=0.023) at the logistic regression analysis. This result was not modified with the propensity analysis.
Conclusion
An excessive chronic ethanol consumption is associated with higher baseline stroke severity.
Am Heart Assoc