BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity and mortality worldwide and is increasing, primarily among women.
Underdiagnosis is common, and because of the heterogeneous disease characteristics,
molecular markers of specific disease phenotypes and more efficacious treatment regimens
are urgently needed. OBJECTIVE: In this study the soluble proteome of bronchoalveolar
lavage cells, primarily consisting of macrophages, was investigated with the aim of …