Oral corticosteroid exposure and adverse effects in asthmatic patients
Background Significant adverse effects (AEs) have been associated with continuous
exposure to oral corticosteroids (OCSs). The potential association with intermittent exposure
is unknown. Objective We sought to assess the association between OCSs and AEs based
on the number of OCS prescriptions. Methods This was a retrospective cohort study of
asthmatic patients 18 years and older in the 2000-2014 MarketScan data set. Propensity
score matching was used at baseline (12 months before the index date: first OCS use) …
exposure to oral corticosteroids (OCSs). The potential association with intermittent exposure
is unknown. Objective We sought to assess the association between OCSs and AEs based
on the number of OCS prescriptions. Methods This was a retrospective cohort study of
asthmatic patients 18 years and older in the 2000-2014 MarketScan data set. Propensity
score matching was used at baseline (12 months before the index date: first OCS use) …