The ladder rung walking task: a scoring system and its practical application.

GA Metz, IQ Whishaw - JoVE (Journal of Visualized Experiments), 2009 - jove.com
Progress in the development of animal models for/stroke, spinal cord injury, and other
neurodegenerative disease requires tests of high sensitivity to elaborate distinct aspects of
motor function and to determine even subtle loss of movement capacity. To enhance efficacy
and resolution of testing, tests should permit qualitative and quantitative measures of motor
function and be sensitive to changes in performance during recovery periods. The present
study describes a new task to assess skilled walking in the rat to measure both forelimb and …