[HTML][HTML] Transcriptome analysis of peripheral blood in chronic inflammatory demyelinating polyradiculoneuropathy patients identifies TNFR1 and TLR pathways in the …

A Richard, JC Corvol, R Debs, P Reach, K Tahiri… - Medicine, 2016 - journals.lww.com
We have studied the response to intravenous immunoglobulins (IVIg) by a transcriptomic
approach in 11 chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients
(CIDP duration= 6 [0.83–6.5] years). RNA was extracted from cells in whole blood collected
before and 3 weeks after IVIg treatment, and hybridized on Illumina chips. After RNA quality
controls, gene expression was analyzed using statistical tests fitted for microarrays (R
software, limma package), and a pathway analysis was performed using DAVID software …