Gene expression profiling in chronic inflammatory demyelinating polyneuropathy

S Renaud, AP Hays, TH Brannagan III… - Journal of …, 2005 - Elsevier
Gene expression in archived frozen sural nerve biopsies of patients with chronic
inflammatory demyelinating polyneuropathy (CIDP) was compared to that in vasculitic nerve
biopsies (VAS) and to normal nerve (NN) by DNA microarray technology. Hierarchical
clustering analysis demonstrated distinct gene expression patterns distinguishing these
disease groups. Of particular interest were:(1) Tachykinin precursor 1, which may be
involved in pain mediation;(2) Stearoyl-CoA-desaturase, which may be a marker for …