Possible association of folic acid supplementation during pregnancy with reduction of preterm birth: a population-based study

AE Czeizel, EH Puho, Z Langmar, N Acs… - European Journal of …, 2010 - Elsevier
OBJECTIVE: Periconceptional folic acid or multivitamin supplementation is recommended
for prospective pregnant women to prevent neural-tube defects. The question is whether it is
worth continuing these supplementations after the first trimester of pregnancy or not. Thus
the possible fetal growth promoting and/or preterm birth reducing effect of vitamin
supplements in the second and mainly in the third trimester was studied. STUDY DESIGN:
Comparison of birth outcomes of singletons born to primiparous pregnant women with …