No teratogenic effect after clotrimazole therapy during pregnancy

AE Czeizel, M Tóth, M Rockenbauer - Epidemiology, 1999 - journals.lww.com
We evaluated the potential teratogenic effects of vaginal and/or topical administration of
clotrimazole in the large population-based dataset of the Hungarian Case-Control
Surveillance of Congenital Abnormalities (1980–1992). The dataset included 18,515 case
pregnancies and 32,804 control pregnancies; 7.1% of case and 7.7% of control women
used clotrimazole during pregnancy. Clotrimazole use was not clearly associated with an
increase in the total (fetal+ birth) prevalence of any congenital abnormality group. There …