Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural
degenerative disease usually caused by gene defects that disrupt the function or
architecture of the photoreceptors. While RP can initially be a disease of photoreceptors,
there is increasing evidence that the inner retina becomes progressively disorganized as the
outer retina degenerates. These alterations have been extensively described in animal
models, but remodeling in humans has not been as well characterized. This study, using …