[HTML][HTML] Critical evaluation of the colocalization between calcitonin gene-related peptide, substance P, transient receptor potential vanilloid subfamily type 1 …

TJ Price, CM Flores - The Journal of Pain, 2007 - Elsevier
Calcitonin gene-related peptide (CGRP) and/or substance P (SP) immunoreactivity as well
as isolectin B4 (IB4) binding are commonly used to define peptidergic and non-peptidergic
nociceptor populations, respectively. Although this demarcation is well supported in the
mouse, there is accumulating evidence to suggest it is not so in the rat. Hence, this
investigation was undertaken to evaluate and quantify the colocalization of the
neuropeptides CGRP and SP with IB4 binding sites and the transient receptor potential …