Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review
Bosnian journal of basic medical sciences, 2014•pmc.ncbi.nlm.nih.gov
Epigenetic mechanisms play a crucial role in cellular proliferation, migration and
differentiation in both normal and neoplastic development. One of the key signaling
pathways whose components are altered through the epigenetic mechanisms is the Wnt
signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and
focus on the recent advances in the Wnt signaling pathway research and its potential
diagnostic and therapeutic implications.
differentiation in both normal and neoplastic development. One of the key signaling
pathways whose components are altered through the epigenetic mechanisms is the Wnt
signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and
focus on the recent advances in the Wnt signaling pathway research and its potential
diagnostic and therapeutic implications.
Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.
pmc.ncbi.nlm.nih.gov
