Flexible colonoscopy in mice to evaluate the severity of colitis and colorectal tumors using a validated endoscopic scoring system
T Kodani, A Rodriguez-Palacios, D Corridoni… - JoVE (Journal of …, 2013 - jove.com
The use of modern endoscopy for research purposes has greatly facilitated our
understanding of gastrointestinal pathologies. In particular, experimental endoscopy has
been highly useful for studies that require repeated assessments in a single laboratory
animal, such as those evaluating mechanisms of chronic inflammatory bowel disease and
the progression of colorectal cancer. However, the methods used across studies are highly
variable. At least three endoscopic scoring systems have been published for murine colitis …
understanding of gastrointestinal pathologies. In particular, experimental endoscopy has
been highly useful for studies that require repeated assessments in a single laboratory
animal, such as those evaluating mechanisms of chronic inflammatory bowel disease and
the progression of colorectal cancer. However, the methods used across studies are highly
variable. At least three endoscopic scoring systems have been published for murine colitis …