Differential reactive oxygen species production of neutrophils and their oxidative damage in patients with active and inactive systemic lupus erythematosus

N Elloumi, RB Mansour, S Marzouk, M Mseddi… - Immunology …, 2017 - Elsevier
Objective Increasing interest is given to the involvement of the innate immunity and
especially Polymorphonuclear neutrophils (PMN) in the physiopathological process of
inflammatory diseases such as systemic lupus erythematosus (SLE). Here, we investigated
the oxidative burst and damages in SLE patients neutrophils, considering the two phases of
the disease, the active and the remission/inactive states. Methods This study was conducted
on 30 SLE patients and 23 healthy controls. The oxidative burst in neutrophils of SLE …