The role of calcium channel blockers in the treatment of essential hypertension
DM Cummings, P Amadio, L Nelson… - Archives of internal …, 1991 - jamanetwork.com
Calcium channel blockers, originally developed for the treatment of angina and
supraventricular arrhythmias, have been shown to lower elevated blood pressure effectively
in hypertensive patients. Verapamil, nifedipine, and diltiazem represent prototype
compounds for unique chemical classes with differing pharmacologic properties. These
drugs lower elevated blood pressure with efficacy comparable with other commonly used
antihypertensives. Combination therapy with other agents usually results in an additive …
supraventricular arrhythmias, have been shown to lower elevated blood pressure effectively
in hypertensive patients. Verapamil, nifedipine, and diltiazem represent prototype
compounds for unique chemical classes with differing pharmacologic properties. These
drugs lower elevated blood pressure with efficacy comparable with other commonly used
antihypertensives. Combination therapy with other agents usually results in an additive …