Vitamins C and E: acute interactive effects on biomarkers of antioxidant defence and oxidative stress
SW Choi, IFF Benzie, AR Collins, BM Hannigan… - Mutation Research …, 2004 - Elsevier
Oxidative stress is implicated in the aetiology of many diseases; however, most
supplementation trials with antioxidant micronutrients have not shown expected beneficial
effects. This randomized, double-blinded, placebo-controlled study evaluated acute effects
(at 90, 180min and 24h [fasting] post-ingestion) of single doses of Vitamins C (500mg) and E
(400IU), alone and in combination, on biomarkers of plasma antioxidant status, lipid
peroxidation and lymphocyte DNA damage in 12 healthy, consenting volunteers. Plasma …
supplementation trials with antioxidant micronutrients have not shown expected beneficial
effects. This randomized, double-blinded, placebo-controlled study evaluated acute effects
(at 90, 180min and 24h [fasting] post-ingestion) of single doses of Vitamins C (500mg) and E
(400IU), alone and in combination, on biomarkers of plasma antioxidant status, lipid
peroxidation and lymphocyte DNA damage in 12 healthy, consenting volunteers. Plasma …
