[HTML][HTML] Longitudinal pulmonary function testing outcome measures in Duchenne muscular dystrophy: long-term natural history with and without glucocorticoids

CM McDonald, H Gordish-Dressman… - Neuromuscular …, 2018 - Elsevier
We describe changes in pulmonary function measures across time in Duchenne muscular
dystrophy patients treated with glucocorticoids (GCs)> 1 year compared to GC naïve patients
in the Cooperative International Research Group Duchenne Natural History Study, a
multicenter prospective cohort study. 397 participants underwent 2799 pulmonary function
assessments over a period up to 10 years. Fifty-three GC naïve participants (< 1 month
exposure) were compared to 322 subjects with> 1 year cumulative GC treatment. Forced …