Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F
X Wang, DM Driscoll, RE Morton - Journal of Biological Chemistry, 1999 - jbc.org
Published studies demonstrate that lipid transfer inhibitor protein (LTIP) is an important
regulator of cholesteryl ester transfer protein (CETP) activity. Although LTIP inhibits CETP
activity among different lipoprotein classes, it preferentially suppresses transfer events
involving low density lipoprotein (LDL), whereas transfers involving high density lipoprotein
as donor are less affected. In this study, we report the purification of LTIP and the expression
of its cDNA in cultured cells. Purification of LTIP, in contrast to other published protocols …
regulator of cholesteryl ester transfer protein (CETP) activity. Although LTIP inhibits CETP
activity among different lipoprotein classes, it preferentially suppresses transfer events
involving low density lipoprotein (LDL), whereas transfers involving high density lipoprotein
as donor are less affected. In this study, we report the purification of LTIP and the expression
of its cDNA in cultured cells. Purification of LTIP, in contrast to other published protocols …
