Structure of plasma sphingadienine

O Renkonen, EL Hirvisalo - Journal of lipid research, 1969 - jlr.org
The dienic long-chain base (sphingadienine) of human plasma sphingomyelins has been
identified as d-erythro-1, 3-dihydroxy-2-amino-4-trans-14-cis-octadecadiene. A similar
sphingosine was also detected in plasma sphingomyelins of rat, rabbit, and cat. The key
reaction in the structural studies was partial reduction of sphingadienine with hydrazine to
cis-14-sphingenine and 4-sphingenine.