Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls
B Ezeh, M Haiman, HF Alber, B Kunz, B Paulweber… - Journal of lipid …, 2003 - jlr.org
Recent studies showed lower apolipoprotein A-IV (apoA-IV) plasma concentrations in
patients with coronary artery disease (CAD). The actual distribution of the antiatherogenic
apoA-IV in human plasma, however, is discussed controversially and it was never
investigated in CAD patients. We therefore developed a gentle technique to separate the
various apoA-IV-containing plasma fractions. Using a combination of precipitation of all
lipoproteins with 40% phosphotungstic acid and 4 M MgCl2, as well as immunoprecipitation …
patients with coronary artery disease (CAD). The actual distribution of the antiatherogenic
apoA-IV in human plasma, however, is discussed controversially and it was never
investigated in CAD patients. We therefore developed a gentle technique to separate the
various apoA-IV-containing plasma fractions. Using a combination of precipitation of all
lipoproteins with 40% phosphotungstic acid and 4 M MgCl2, as well as immunoprecipitation …