High-density lipoprotein subclasses and their relationship to cardiovascular disease
HR Superko, L Pendyala, PT Williams… - Journal of clinical …, 2012 - Elsevier
OBJECTIVE: To assess the clinical utility of measuring high-density lipoprotein (HDL)
subfractions to assess coronary heart disease (CHD) risk. METHODS: Literature review of
80 published investigations. RESULTS: Measurements of HDL2b by gradient gel
electrophoresis provided more consistent evidence of CHD risk than measurement of HDL2
cholesterol. Five of the seven studies that compared the extent or progression of
atherosclerosis with gradient gel electrophoresis estimates of HDL subclasses (71%) …
subfractions to assess coronary heart disease (CHD) risk. METHODS: Literature review of
80 published investigations. RESULTS: Measurements of HDL2b by gradient gel
electrophoresis provided more consistent evidence of CHD risk than measurement of HDL2
cholesterol. Five of the seven studies that compared the extent or progression of
atherosclerosis with gradient gel electrophoresis estimates of HDL subclasses (71%) …
