The identification of tumor related cell membrane protein targets is important in
understanding tumor progression, the development of new diagnostic tools, and potentially
for identifying new therapeutic targets. Here we present a novel strategy for identifying
proteins that are altered in their expression levels in a diseased cell using cell specific
aptamers. Using an intact viable B-cell Burkitt's lymphoma cell line (Ramos cells) as the
target, we have selected aptamers that recognize cell membrane proteins with high affinity …