[HTML][HTML] Plasma membrane transporters for arginine

EI Closs, A Simon, N Vékony, A Rotmann - The Journal of nutrition, 2004 - Elsevier
The supply of arginine may become rate limiting for enzymatic reactions that use this
semiessential amino acid as a substrate (eg, nitric oxide, agmatine, creatine, and urea
synthesis), particularly under conditions of high demand such as growth, sepsis, or wound
healing. In addition, arginine acts as a signaling molecule that regulates essential cellular
functions such as protein synthesis, apoptosis, and growth. In the past decade, a number of
carrier proteins for amino acids have been identified on the molecular level. They belong to …