Human papillomavirus typing of verrucae in a patient with WHIM syndrome

MD Palm, SK Tyring, PL Rady… - Archives of …, 2010 - jamanetwork.com
Most patients have a specific, poorly understood susceptibility to HPV-induced warts, usually
manifesting in the second decade of life. 8 Warts are recurrent and recalcitrant to treatment,
4 requiring aggressive management. However, the availability of recombinant protein
vaccines against specific HPV subtypes may provide a preventive measure for WHIM-
related HPV infections. 9 Unfortunately, we currently have only a modest understanding of
the B-cell defects in WHIM syndrome, and so the efficacy of HPV vaccination is unknown …