Leptin, adiponectin, and asthma: findings from a population-based cohort study
TJT Sutherland, MR Sears, CR McLachlan… - Annals of Allergy …, 2009 - Elsevier
BACKGROUND: Obesity is thought to increase the risk of asthma, especially in women. It
has been proposed that this association could be due to the immune-modulating effect of
adipokines secreted by adipose tissue. OBJECTIVE: To investigate whether aspects of the
asthma phenotype are associated with higher levels of the proinflammatory adipokine leptin
and lower levels of the anti-inflammatory adipokine adiponectin in a cross-sectional analysis
of a group of young adults. METHODS: Associations between leptin and adiponectin and a …
has been proposed that this association could be due to the immune-modulating effect of
adipokines secreted by adipose tissue. OBJECTIVE: To investigate whether aspects of the
asthma phenotype are associated with higher levels of the proinflammatory adipokine leptin
and lower levels of the anti-inflammatory adipokine adiponectin in a cross-sectional analysis
of a group of young adults. METHODS: Associations between leptin and adiponectin and a …
